Schultes analyzes RNA folding patterns using the tools of NKS. The experimental variable is the informational content of the molecule. He has a robot for creating tailor made RNA sequences. The result of their experiment was that arbitrary sequences acquire sequence-specific folds. Also they used the technique of native gel electrophoresis. More compact sequences migrate faster.
He wants to examine the space of all possible sequences and examine the distribution of folds in RNA sequence space.
(It was a very interesting talk I don't think I've done justice to. Right afterwards I quickly ate some lunch and went upstairs to take a nap and let my brain rest up a bit.)
Abstract. His website is at hedgehogresearch.info.
Comments